This image has survived to the present, a blank canvas onto which any theory can be projected. When these hopes faded, Cullen became a figure obsessed with the nerves. Moreover, this article examines how Cullen’s standing fell in the 1820s as British physicians and surgeons turned to an idea which promised to reform medicine: pathological anatomy. The result is a more complicated version of neurosis which, importantly, carries significant insights into the nature and practice of medicine. This article attempts to subvert this process, by rebuilding the original meaning of neurosis through Cullen’s physiological and medical works, in comparison with his predecessor, Robert Whytt (1714–66), and illustrating this meaning using one particular neurosis: hypochondriasis. William Cullen (1710–90), whose work on neurosis was once part of the history of psychoanalysis, is now well placed to become part of such a neuro-history.
History is being rewritten with the brain as its centrepiece the search for great men and big ideas of the past begins again. Existential questions – about who we are, about our origins and future, about what is valuable – no longer require difficult soul searching, especially when straightforward answers are expected from the neurosciences.
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